Prenatal BoBs, a more informative option than FISH and QF-PCR for IVD labs

Prenatal BoBs™ is a CE-marked IVD product based on BACs-on-Beads technology. In addition to detecting copy number changes of chromosomes 13, 18, 21, X and Y, the product enables detection of 9 additional chromosomal regions in which a clear correlation between a loss and an adverse outcome has been demonstrated.1 Copy number changes in these targeted microdeletion regions are not easily found with other commonly used methods. Also the microdeletion syndromes detected by Prenatal BoBs often are not inherited and do not display ultrasound abnormalities, so they may otherwise be missed in a prenatal setting.