ViennaLab focus is on product development, promoting original IVD StripAssays®, RealFast™ and NGS assays.
ViennaLab products offer differentiated options, presenting customized solutions for genetic testing. From simple and rapid single marker detection to complex genetic analysis.
- Genetic Disorders
- Genetic Predispositions
- Somatic pathogenic variants in BRAF, EGFR, KRAS and NRAS genes may influence cancer therapies. The identification of such pathogenic variants in these genes allows targeted treatment and stratification of cancer patients.
- Genetic variants of genes involved in drug metabolism (e.g. DPYD and TPMT) can significantly alter the response to chemotherapeutic treatment.
- The impact of specific genetic variants are covered in current guidelines for the respective type of cancer.
- Genetic abnormalities range from variations in single genes or a group of genes to the gain or loss of an entire chromosome or set of chromosomes.
- The responsible/causative genetic variants are either inherited from the parents or acquired during a person´s life.
- Patterns of inheritance include single gene inheritance, polygenic (multifactorial) inheritance, chromosomal abnormalities and mitochondrial inheritance.
- ViennaLab provides rapid and robust tests for diagnosis of mono- or polygenic disorders.
- A genetic predisposition is an often inherited genetic change which contributes to the development of a disease but does not directly cause it.
- Genetic modifiers, lifestyle and environmental factors may increase the risk.
- Several genetic alterations are known to enhance an individual’s susceptibility to illnesses like cardiovascular diseases, Alzheimer´s disease, ankylosing spondylitis (Morbus Bechterew) and cancer.
- Early diagnosis is crucial for timely onset of treatment, maintaining life quality and life expectancy.
- Genetic polymorphisms / aberrations in metabolic pathways often result in an altered response to drugs.
- Increasing knowledge on the effect of genetic variations in drug metabolizing enzymes is available, paving the way for a personalized medicine.
- With the help of ViennaLab assays it is possible to determine who will benefit from a medication, who will poorly or not respond at all, and who may experience adverse drug reactions.